- Title
- Glucose sensor using redox active oligonucleotide-templated silver nanoclusters
- Creator
- Schroeder, Kathryn L.; Goreham, Renee V.; Nann, Thomas
- Relation
- Nanomaterials Vol. 9, Issue 8
- Publisher Link
- http://dx.doi.org/10.3390/nano9081065
- Publisher
- MDPI AG
- Resource Type
- journal article
- Date
- 2019
- Description
- Redox active, photoluminescent silver nanoclusters templated with oligonucleotides were developed for glucose sensing. The silver nanoclusters had a photoluminescent emission at 610 nm that reversibly changed to 530 nm upon oxidation. The reversible emission change was measured with photoluminescent spectroscopy and used to detect H₂O₂, which is a by-product of the reaction of glucose with glucose oxidase. The ratio of the un-oxidised emission peak (610 nm) and the oxidised analogue (530 nm) was used to measure glucose concentrations up to 20 mM, well within glucose levels found in blood. Also, the reversibility of this system enables the silver nanoclusters to be reused.
- Subject
- nanocluster; silver; glucose; photoluminescence; DNA; oxidation; biosensing; reversible
- Identifier
- http://hdl.handle.net/1959.13/1408331
- Identifier
- uon:35827
- Identifier
- ISSN:2079-4991
- Rights
- This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Language
- eng
- Full Text
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